Antibody e Neutralization

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Tlhaloso e Khutšoanyane:

SARS-CoV-2 ke kokoana-hloko ea RNA e apesitsoeng le e le 'ngoe, e leng ea mofuta oa beta.cov lelapeng la coronaviridae.1ts genome RNA e kenyelletsa protheine e se nang sebopeho le liprotheine tse 'maloa tsa sebopeho, ho kenyeletsoa li-spike(s), enfelopo(E), membrane(M) le liprotheine tsa nucleocapsid(N).

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Pathogenesis:

Protheine ea S e ikarabella bakeng sa kokoana e tlamang le ho kena ka har'a lisele tse amohelang, tse nang le likaroloana tse peli tse sebetsang, s1 le s2 le domain binding domain (RBD) e teng ka har'a li-subunits tsa s1. RBD ea SARS-CoV-2 S protheine e sebelisana. e nang le angiotensin e fetolang enzyme 2 (AcE2), e bakang liphetoho tse amanang le karoloana ea s2 e hlahisang

ho kopanngoeng ke kokoana-hloko le ho kena ka har'a sele e lebeletsoeng .Li-protease tsa lekunutu tsa batho, joalo ka TMPRss2 le furin, li fumaneha ho li-virally.targets cell.

Li-protease tsena li ntlafatsa ho kena ha kokoana-hloko liseleng tse amohelang batho ka proteolysis ea liprotheine tsa s1, s2, le AcE2 ka bobeli.

Tšebeliso e nepahetseng:

Anti SARS-CoV-2 Neutralizing Antibody Rapid Test Kit e etselitsoe tlhahlobo ea in vitro ea li-antibodies tsa SARS-CoV-2 tse fokotsang lisampole tsa mali a motho.SARS-CoV-2 Neutralizing antibody ke letšoao la bohlokoa bakeng sa ho lekola katleho ea liente tsa SARS-CoV-2.Sehlahisoa sena ke sa ho fokotsa ts'oaetso ea sesole sa 'mele ho disampole ho tsoa ho batho ka mor'a ente ea ente kapa ho hlaphoheloa ho tsoa ho coV1D.19.Setsi sena se tla thusa hape liphuputsong tsa hajoale tsa coV1D.19 tsa ho ata ha sero, tlhahlobo ea ho itšireletsa ha mehlape, nako e telele ea ho itšireletsa mafung, ho sebetsa hantle ha batho ba fapaneng ba enteng hammoho le ho sala morao tšoaetso liphoofolong.

maemo a polokelo le ho sebetsa:

Li-reagents tsohle li loketse ho sebelisoa joalo ka ha li fanoe.Lisebelisoa tsa reagent tse sa buloang li tsitsitse ho 4"c ～30"c bakeng sa likhoeli tse 24 ka nakoana.1t e lokela ho sebelisoa nakong ea hora e le 'ngoe hang ha mokotla o butsoe.Se ke oa hatsetsa khiti kapa ua pepesa khiti ka holimo ho 37"c nakong ea polokelo.

Tlhaloso:

1 teko / lebokose;5 liteko / lebokose;25 liteko / lebokose;50 liteko / lebokose.

Mokhoa oa Teko:

U se ke ua bula mokotla ho fihlela u se u itokiselitse ho etsa tlhahlobo, 'me tlhahlobo ea single.use e khothaletsoa hore e sebelisoe tlas'a mongobo o tlase oa tikoloho (RHs70%) nakong ea hora e le 'ngoe.

1.Lumella lisebelisoa tsohle tsa kit le mehlala ho fihlela mocheso oa kamore pakeng tsa 18"c～26"c pele ho tlhahlobo.2.Tlosa karete ea teko ho tloha mokotleng oa foil 'me u e behe sebakeng se hloekileng se omeletseng.

3.1 tsebahatsa karete ea tlhahlobo bakeng sa mohlala o mong le o mong.

4.Sebelisa dropper ho fana ka lerotholi le le leng (1) la serum, plasma kapa lisele tse feletseng tsa mali (40uL) ka har'a sampuli hantle ka karete ea teko, e lateloa ke lerotholi le le leng la sampuli ea bufer.

5. qala sebali sa nako 'me u bale sephetho ka mor'a metsotso e 15.

Tlhaloso ea Sephetho sa Teko:

1 toloka sephetho sa tlhahlobo ho latela chate e latelang ea mebala (Joalo ka tlase).

1.1f matla a 'mala a tlase ho feta G4, ho bonts'a hore khatello ea antibody e fokolang e kholo ho feta 200 PRNT50 2.1f matla a mebala a pakeng tsa G4 le G6, e leng se bontšang hore mahloriso a anti-antibody a haufi le 100 PRNT50 3.1f matla a 'mala a haufi le G7 , ho bonts'a hore mahloriso ke a antibody a fokolang ke 50 PRNT50

4.Moeli oa ho lemoha ke 50 PRNT50

5.f matla a 'mala a matla ho feta G7, bontša sephetho se fosahetseng.

E fetileng: Automatic Digital Wrist Blood Pressure Monitor

E 'ngoe: Bukana-PocRoc®SARS-CoV-2 Antigen Rapid Test K0429